Editorial Commentary: Platelet-Rich Fibrin Matrix-Is This Stuff for Real?!
Authors
Lall AC, Domb BG
Journal: Arthroscopy. 2018 Mar;34(3):842-843.
DOI: 10.1016/j.arthro.2017.10.018
PMID: 29502702
Background
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have become popular treatments for tendon and joint pathology, but the clinical evidence remains mixed.
Methods
The authors review the use of PRF and PRP in orthopedics, addressing the placebo effect, patient psychology, and the costs associated with these biologic treatments.
Key Findings
While PRF and PRP are widely used, their true effectiveness may be influenced by psychological factors and patient expectations. Evidence for their efficacy is variable.
Conclusions
The clinical benefits of PRF and PRP are still unclear, and clinicians should consider the placebo effect and patient expectations when prescribing these treatments.
What Does This Mean for Patients
Patients should be aware that the effectiveness of PRF and PRP may vary, and their treatment outcomes could be influenced by psychological factors as well as the biological properties of the treatments.